Course Title Carbohydrate And Nucleic Acid Metabolism
Course Level 200
Credit Unit 2

INTRODUCTION 

Digestion is the process in which the body breaks down carbohydrate, protein, and triglyceride polymers into their monomer residues. Digestion occurs in the digestive system. The digestive system, sometimes referred to as the digestive track or gastrointestinal (GI) track, includes the organs that are responsible for digesting food and eliminating the indigestible components of food. During the digestion of carbohydrate polymers, most oligosaccharides (2-10 monosaccharide residues) and polysaccharides (> 10 monosaccharide residues) can be broken down to monosaccharide (glucose) which is required for energy generation. 


Nucleic acids on the other hand are biopolymers that are involved in the preservation/storage and transmission of genetic information from one generation to another. 

COURSE CONTENTS

This course is divided into two parts: 

  1. Carbohydrate metabolism

Students will be taught 

  • Degradation and digestion of carbohydrates; sugars 

  • Pathways of carbohydrate digestion; glycolysis, Citric Acid Cycle, Gluconeogenesis. the phosphogluconate pathway, the glyoxylic acid cycle, the pentose phosphate pathway, cori cycle, the Calvin pathway, Glucogenesis, glycogenesis and glycogenolysis

  • Regulation of Carbohydrate metabolism.

  • Disorders of carbohydrate metabolism


  1. Nucleic acids Metabolism

Students will be taught:

  • What nucleic acids are, bases and base pairing

  • Purine and pyrimidine synthesis and catabolism and their regulations

  • Abnormalities in nucleic acid metabolism, xeroderma, gout, skin cancer, etc.

EXPECTATIONS

At the end of the course, the student is expected to:

  1. Understand the degradation and complete digestion of carbohydrates via different biochemical pathways.

  2. Gain knowledge on  Purine and pyrimidine synthesis and catabolism

  3. Describe different means of metabolism regulation of carbohydrate and nucleic acids

  4. Identify different disorders associated with carbohydrate and nucleic acids metabolism